“Sub Tuum Praesidium” (Latin for “Under thy protection”; Greek: Ὑπὸ τὴν σὴν εὐσπλαγχνίαν) is the oldest extant hymn yet discovered to the Theotokos (Mother of God).

Latin Text

Sub tuum praesidium confugimus, Sancta Dei Genitrix.
Nostras deprecationes ne despicias in necessitatibus nostris,
sed a periculis cunctis libera nos semper,
Virgo gloriosa et benedicta.

English Translation

Under thy protection we seek refuge, O Holy Mother of God;
In our needs, despise not our petitions,
but deliver us always from all dangers,
O Glorious and Blessed Virgin.