"All the reprobate have been damned in consequence of their neglect of prayer; had they prayed they should not be lost; and all the saints have become saints by prayer; had they neglected prayer, they would not have become saints.  We must live in the persuasion, St. John Chrysostom says, that to neglect prayer, and to lose the grace of God, are one and the same thing." 
St. Alphonsus